BIOL 204 – Biochemistry
MIDTERM EXAM 2: 100 POINTS
APRIL 5th, 2016
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BIOL 204 – Biochemistry Name:
SPRING 2016/REA Penn ID (middle 8 digits):
1. For the uncatalyzed reaction:
k1
S ⇌ P
k-1
k1 = 100 and k-1 = 10.
If an enzyme were to catalyze this reaction and increase its rate by 10,000-fold it
follows that:
(6 pts)
A. Keq(catalyzed) = 10
B. Keq(catalyzed) = 106
C. k-1(catalyzed) = 10
D. k-1(catalyzed) = 105
E. -ΔG(S → P) increases four-fold
2. The expression for a simple single-substrate enzyme-catalyzed reaction: